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KMID : 0942820020010020173
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Journal of Korean Brain Tumor Society
2002 Volume.1 No. 2 p.173 ~ p.176
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Multiple Intraorbital and Intracranial Germinoma Primary
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Yoe In-Sung
Lee Sang-Won
Woo Hee-Kyung
Sung Jae-Hoon
Choi Seung-Jin
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Abstract
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We report the unusual case of multiple intraorbital and intracranial germinoma primarily arising from optic nerve, pineal gland extending to the splenium of corpus callosum. The patient was 27-year-old male who presented with progressinve bilateral visual loss for 2yrs and suddenly developed right painful exothalmus. The neuroimaging studies disclosed tumors in the right optic nerve, optic chiasm, pineal gland and posterior corpus callosum. The tumor markers of serum and cerebrospinal fliud were all negative. The intraorbital and intracranial optic nerve tumor was removed via fronto-orbitotomy and pterional approach. The histological diagnosis was germinoma. Follow up brain MRI demonstrated complete disappearance of the multiple masses after completion of three courses of combinant chemotheraphy with Ifosfamide-Cisplatin-Etoposide. This case is believed to be the first case report as multiple intraorbital and intracranial primary germinoma.
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KEYWORD
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Optic nerve, Germinoma, Combinant chemotheraphy
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